New hydroxamate metabolite, MBJ-0003, from Micromonospora sp. 29867
نویسندگان
چکیده
منابع مشابه
A new anthracycline antibiotic micromonomycin from Micromonospora sp.
In the course of our continuing search for novel antimicrobial agents,1-5) we have isolated a novel antibacterial anthracycline, micromonomycin (1), from culture Micromonospora sp. Micromonomycin was identified as a new anthracycline using high resolution ESIMS and extensive NMR spectroscopic analyses. In this paper, we describe the isolation and structure elucidation of 1. The biological activ...
متن کاملMicromonospora lupini sp. nov. and Micromonospora saelicesensis sp. nov., isolated from root nodules of Lupinus angustifolius.
A study was conducted to determine the taxonomic status of six actinomycete strains isolated from root nodules of Lupinus angustifolius. The strains were filamentous, Gram-positive and produced single spores at the tip of the hyphae. Phylogenetic, chemotaxonomic and morphological analyses demonstrated that all six strains belonged to the genus Micromonospora. According to the 16S rRNA gene sequ...
متن کاملMicromonospora mirobrigensis sp. nov.
An actinomycete strain was recovered from a pond where radon is known to be dissolved. A polyphasic study was undertaken to identify the new isolate. The 16S rRNA gene sequence of strain WA201(T) showed closest similarity to the type strains of Micromonospora carbonacea (98.5 %) and Micromonospora matsumotoense (98.1 %). The chemotaxonomic results confirmed the taxonomic position of the isolate...
متن کاملR176502, a new bafilolide metabolite with potent antiproliferative activity from a novel Micromonospora species.
During the course of a screening program intended to identify new antiproliferative agents, a new bafilolide metabolite was discovered. R176502 (1) was isolated from the liquid fermentation cultures of a novel Micromonospora species found in African river bottom sediment. It was purified from ethyl acetate extracts using a series of countercurrent chromatographic steps. The structure was determ...
متن کاملLuteophanol D, New Polyhydroxyl Metabolite from Marine Dinoflagellate Amphidinium sp
Luteophanol D (1), a new polyhydroxyl linear carbon-chain metabolite, has been isolated from the cultured marine dinoflagellate Amphidinium sp., which was isolated from Okinawan marine acoel flatworm Pseudaphanostoma luteocoloris. The structure of 1 was elucidated by detailed analyses of 2D NMR spectra. Luteophanol D (1) possesses two tetrahydropyran rings and twenty-three hydroxyl groups on C6...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 2013
ISSN: 0021-8820,1881-1469
DOI: 10.1038/ja.2013.124